Steroids and derivatives
Apexbio Technology LLC Cortisone acetate 50-04-4 500mg
Cortisone acetate (50-04-4) is a glucocorticoid receptor agonist targeting the glucocorticoid receptor It is designed to modulate glucocorticoid signaling thereby regulating gene transcription and downstream immune and inflammatory responses Cortisone acetate exerts its biological activity primarily through enzymatic conversion to cortisol which subsequently activates glucocorticoid receptors to influence cellular stress and inflammatory pathways Based on these pharmacological properties cortisone acetate holds research potential in the investigation of glucocorticoid signaling pathways receptor-mediated transcriptional regulation cellular stress responses and inflammatory condition models
Medchemexpress LLC Alogliptin-d3 | 1133421-35-8 | 99.6% | C18H18D3N5O2 | 5 MG
Alogliptin-d3 is the deuterium labeled Alogliptin, a potent, selective, and orally active inhibitor of DPP-4 with an IC50 of <10 nM. It exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9 and can be used for the research of type 2 diabetes. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for quantitation during drug development and can influence pharmacokinetic and metabolic profiles.
- Deuterium labeled Alogliptin.
- Potent, selective, and orally active inhibitor of DPP-4.
- Exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
- Suitable for research of type 2 diabetes.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Cinacalcet-d3 hydrochloride | 364782-34-3 | 97.6% | C22H20D3ClF3N | 500 UG
Cinacalcet-d3 (hydrochloride) is the deuterium labeled Cinacalcet (hydrochloride). It is an orally active, allosteric agonist of the Ca receptor (CaR), used for cardiovascular disease treatment. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Isotope-labeled compound.
- Endogenous metabolite.
- Inhibitor.
- Targets CaSR and is relevant for cardiovascular disease.
Selleck Chemical LLC Vitamin A Acetate S4083-50mg
Vitamin A Acetate (Retinyl Retinol) is a group of unsaturated nutritional hydrocarbons that includes retinol retinal retinoic acid and several provitamin A carotenoids among which beta-carotene is the most important
Cambridge Isotope Laboratories Melatonin (acetyl-D3 98%) CP 95% 10 mg
Melatonin (acetyl-D3 98%) CP 95% 10 mg
Medchemexpress LLC Hydrocortisone acepo 10mg | 74050-20-7 | 460.56 g/mol | C26H36O7 | 10 MG
Hydrocortisone aceponate (hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid supplied for research use in studies of dermatoses and glucocorticoid receptor biology.
- Potent topical glucocorticoid for dermatoses research.
- White to off-white powder appearance.
- Purity approximately 99.4% as stated by supplier.
- Chemical formula C26H36O7; molecular weight 460.56 g/mol.
- Available as solids (5 mg, 10 mg, 25 mg, 50 mg) and as a 10 mM solution in DMSO (1 mL).
- Soluble in DMSO (~100 mg/mL); ultrasonic treatment recommended.
- Storage: powder -20°C (stable ~3 years) or 4°C (stable ~2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or veterinary use.
Selleck Chemical LLC Cortisone
Cortisone is a pregnane steroid hormone and one of main substance released by the body as a reaction to stress It suppresses the immune system thus reducing inflammation and attendant pain and swelling at the site of the injury
Medchemexpress LLC Resolvin D2 | 810668-37-2 | 99.9% | 376.49 | 25 UG
Resolvin D2 is a metabolite derived from docosahexaenoic acid (DHA) that exhibits anti-inflammatory and anti-infective properties. It acts as a potent regulator of leukocytes and is effective in controlling microbial sepsis. This compound also functions as a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons.
- Anti-inflammatory activities
- Anti-infective activities
- Leukocyte regulation
- Control of microbial sepsis
- TRPV1 and TRPA1 inhibition
- Resolution of inflammation and tissue regeneration
- Decreases leukocyte:endothelial interactions
- Inhibits inflammatory pain
Medchemexpress LLC Hexanoylglycine-d2 | 1256842-52-0 | 175.22 | 100 MG
Hexanoylglycine-d2 | 1256842-52-0 | 175.22 | 100 MG
Medchemexpress LLC Bazedoxifene (acetate)-D | 198481-33-3 | MFCD09260074 | C32H38N2O5 | 100 MG
Bazedoxifene (acetate)-D is a solid compound with a molecular formula of C32H38N2O5 and a molecular weight of 530.65. It is classified as a selective estrogen receptor modulator and a bone density conservation agent. This compound helps to inhibit bone resorption and favor bone mineralization, making it suitable for addressing conditions like osteoporosis and promoting bone fracture healing. It is an FDA-approved, prescription-only drug administered orally.
- Functions as a selective estrogen receptor modulator
- Acts as a bone density conservation agent
- Inhibits bone resorption
- Promotes bone mineralization and regeneration
- Utilized in treating osteoporosis and healing bone fractures
- FDA-approved, available by prescription only
- Administered via oral route